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Understanding Cingulum Lateralization in TBI: Implications for Practitioners

Understanding Cingulum Lateralization in TBI: Implications for Practitioners

Introduction

Traumatic brain injury (TBI) remains a critical concern in military populations, often leading to disruptions in brain structure and function. A recent study titled "Altered lateralization of the cingulum in deployment-related traumatic brain injury: An ENIGMA military-relevant brain injury study" provides significant insights into how TBI affects the brain's white matter, particularly the cingulum. This blog aims to translate these findings into practical applications for practitioners, enhancing their ability to support individuals with TBI.

Key Findings of the Study

The study conducted a mega-analysis involving 2,598 Active Duty Service Members and Veterans, utilizing diffusion magnetic resonance imaging (dMRI) to examine white matter (WM) microstructure. The researchers discovered greater asymmetry in the cingulum among individuals with deployment-related TBI, characterized by increased left lateralization. This asymmetry was not influenced by confounding factors such as posttraumatic stress disorder, depression, or handedness. Notably, the findings were most pronounced in individuals whose worst TBI occurred before the age of 40.

Implications for Practitioners

Understanding the lateralization of the cingulum and its impact on cognitive function is crucial for practitioners working with TBI patients. Here are some practical steps practitioners can take based on the study's findings:

Encouraging Further Research

While the study provides valuable insights, it also opens avenues for further research. Practitioners are encouraged to explore the following areas:

Conclusion

The study on cingulum lateralization in TBI offers critical insights that can significantly enhance the practice of speech-language pathologists and other healthcare providers. By integrating these findings into clinical practice, practitioners can improve outcomes for individuals affected by TBI. For those interested in delving deeper into the research, the original study provides a comprehensive overview of the methodologies and findings.

To read the original research paper, please follow this link: Altered lateralization of the cingulum in deployment-related traumatic brain injury: An ENIGMA military-relevant brain injury study.


Citation: Dennis, E. L., Newsome, M. R., Lindsey, H. M., Adamson, M., Austin, T. A., Disner, S. G., Eapen, B. C., Esopenko, C., Franz, C. E., Geuze, E., Haswell, C., Hinds, S. R. II, Hodges, C. B., Irimia, A., Kenney, K., Koerte, I. K., Kremen, W. S., Levin, H. S., Morey, R. A., ... Wilde, E. A. (2023). Altered lateralization of the cingulum in deployment-related traumatic brain injury: An ENIGMA military-relevant brain injury study. Human Brain Mapping, 44(5), 1888–1900. https://doi.org/10.1002/hbm.26179
Marnee Brick, President, TinyEYE Therapy Services

Author's Note: Marnee Brick, TinyEYE President, and her team collaborate to create our blogs. They share their insights and expertise in the field of Speech-Language Pathology, Online Therapy Services and Academic Research.

Connect with Marnee on LinkedIn to stay updated on the latest in Speech-Language Pathology and Online Therapy Services.

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